Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1500713 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1KEAP1NFE2L2 | |
| SCHEMBL8412113 | 0.80 | MAPT (0.38) | ALDH1A1SMN1; SMN2TSHRMAPTL3MBTL1 | |
| SCHEMBL8409405 | 0.79 | PKM (0.39) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8411651 | 0.79 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KMT2ATSHRMAPT | |
| SCHEMBL8411647 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KMT2ATSHRMAPT | |
| SCHEMBL8409383 | 0.78 | GABRA1 (0.36) | ALDH1A1SMN1; SMN2KMT2ATSHRMAPT | |
| SCHEMBL28740531 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2ATSHRMAPT | |
| SCHEMBL8409259 | 0.75 | CCR2 (0.36) | ALDH1A1SMN1; SMN2KMT2ATSHRCCR2 | |
| SCHEMBL7101521 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8410786 | 0.74 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2KMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |