Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410344 | 0.92 | ALDH1A1 (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8630560 | 0.86 | GRIN2D (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8413370 | 0.82 | MEN1 (0.32) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL453784 | 0.81 | ALDH1A1 (0.32) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7627856 | 0.77 | CES2 (0.35) | TDP1 | |
| SCHEMBL8822878 | 0.76 | FDPS (0.40) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL3001830 | 0.73 | CES2 (0.44) | MEN1KMT2A | |
| SCHEMBL8413329 | 0.72 | MEN1 (0.30) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL8414197 | 0.72 | MEN1 (0.30) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL8633890 | 0.70 | LAP3 (0.32) | MEN1LMNAHPGDTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690049-B1 | Agent for treating hepato biliary diseases | R TECH UENO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| US-5739161-A | PROSTAGLANDINS; DIARRHEA SIDE EFFECT REDUCTION | R-TECH UENO, LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0690049-A2 | Agent for treating hepato biliary diseases | R-TECH UENO LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |