Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520382 | 0.94 | KDM4E (0.58) | PKMKDM4EALDH1A1KMT2A | |
| SCHEMBL8414084 | 0.89 | PARP1 (0.53) | KDM4ESMN1; SMN2KMT2ATSHRHPGD | |
| SCHEMBL7497881 | 0.80 | PKM (0.71) | PKMKDM4EUSP2ALDH1A1MAPK1 | |
| SCHEMBL2749472 | 0.78 | KMT2A (0.65) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8413952 | 0.78 | GRIA2 (0.53) | PKMKDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL8413733 | 0.75 | LMNA (0.49) | PKMKDM4EUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30007934 | 0.73 | KDM4E (0.86) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL21247083 | 0.73 | KDM4E (0.86) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8414072 | 0.73 | MAPT (0.47) | ALDH1A1SMN1; SMN2KMT2ATSHRHPGD | |
| SCHEMBL9620317 | 0.72 | PKM (0.56) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912245-A | AMPA AND KAINATE ANTAGONISTS. | EGIS GYOGYSZERGYAR RT. (HU) | 1999-06-15 | — | — | US | disclosed |