Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415265 | 0.94 | PKM (0.56) | KDM4EALDH1A1KMT2APKM | |
| SCHEMBL8414084 | 0.83 | PARP1 (0.53) | KDM4EKMT2AMAPTCYP3A4 | |
| SCHEMBL1961249 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1KMT2APOLBPKM | |
| SCHEMBL8413952 | 0.76 | GRIA2 (0.53) | KDM4EALDH1A1KMT2APKMMAPT | |
| SCHEMBL8414072 | 0.76 | MAPT (0.47) | ALDH1A1KMT2AMAPTCYP3A4 | |
| SCHEMBL7497881 | 0.74 | PKM (0.71) | KDM4EALDH1A1KMT2APOLBPKM | |
| SCHEMBL9620614 | 0.73 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2APOLBPKM | |
| SCHEMBL8413733 | 0.73 | LMNA (0.49) | KDM4EALDH1A1KMT2APOLBPKM | |
| SCHEMBL9620583 | 0.73 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2APOLBPKM | |
| SCHEMBL2749472 | 0.72 | KMT2A (0.65) | KDM4EALDH1A1KMT2APKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912245-A | AMPA AND KAINATE ANTAGONISTS. | EGIS GYOGYSZERGYAR RT. (HU) | 1999-06-15 | — | — | US | disclosed |