SCHEMBL841548

SCHEMBL841548

CC(C)(C)c1cccc(OBOc2cccc(C(C)(C)C)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SOD1 P00441 1/20 0.44
LMNA P02545 2/20 0.43
HTT P42858 2/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
KIF11 P52732 1/20 0.40
ACHE P22303 3/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
GRM2 Q14416 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17343658 0.84 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL18118971 0.80 CYP3A4 (0.59) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL28407343 0.80 CYP3A4 (0.50) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL4513039 0.80 JAK2 (0.36) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL289310 0.79 TSHR (0.47) LMNAPOLBL3MBTL1ALDH1A1HSD17B10
SCHEMBL146154 0.78 ACHE (0.52) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL15576545 0.78 CYP3A4 (0.57) CYP3A4CYP2C9CYP2C19SOD1LMNA
SCHEMBL2569034 0.78 CYP4F2 (0.44) CYP3A4CYP2C9CYP2C19POLBNPC1
SCHEMBL1679451 0.78 GABRA1 (0.44) POLBRXRARXRBALDH1A1HPGD
SCHEMBL15889136 0.77 CYP3A4 (0.47) CYP3A4CYP2C9CYP2C19SOD1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP disclosed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US disclosed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-1981898-B2 Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices UNIVERSAL DISPLAY CORP (US) 2019-04-10 EP disclosed
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-21 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
EP-2399922-A1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof Universal Display Corporation (US) 2011-12-28 EP disclosed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US disclosed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US disclosed
EP-2243785-A1 Phosphorescent condensed ring carbene metal complexes for use in organic light emitting devices Universal Display Corporation (US) 2010-10-27 EP disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
EP-1981898-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZOÝ1,2-f¨PHENANTHRIDINE AND DIIMIDAZOÝ1,2-A:1',2'-C¨QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2008-10-22 EP disclosed
WO-2007095118-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2007-08-23 WO disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF NDUFC1, CD274, CRY1 CYP3A4 919/4885CYP2C9 1298/4885CYP2C19 1462/4885
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 CYP3A4 1405/4885CYP2C9 1534/4885CYP2C19 1812/4885
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 CYP3A4 1405/4885CYP2C9 1534/4885CYP2C19 1812/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 CYP3A4 1428/4885CYP2C9 2444/4885CYP2C19 3168/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C CYP3A4 1210/4885CYP2C9 1618/4885CYP2C19 1878/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 CYP3A4 1405/4885CYP2C9 1534/4885CYP2C19 1812/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 CYP3A4 1405/4885CYP2C9 1534/4885CYP2C19 1812/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 CYP3A4 1428/4885CYP2C9 2444/4885CYP2C19 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.