SCHEMBL1679451

SCHEMBL1679451

CC(C)(C)c1cc(OBOc2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
POLB P06746 1/20 0.36
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
HTR1D P28221 1/20 0.31
HMGCR P04035 2/20 0.31
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1543020 0.87 POLB (0.35) GABRA1GABRB2POLBRXRARXRB
SCHEMBL17191780 0.81 GABRA1 (0.46) GABRA1GABRB2POLBMAPTKDM4E
SCHEMBL841548 0.78 CYP3A4 (0.46) POLBMAPTRXRARXRBALDH1A1
SCHEMBL452367 0.77 MAPT (0.52) POLBMAPTKDM4EALDH1A1HPGD
SCHEMBL521971 0.75 IDO1 (0.40) MAPTRXRARXRBRXRGALDH1A1
SCHEMBL93161 0.74 GABRA1 (0.69) GABRA1GABRB2POLBMAPTKDM4E
SCHEMBL3807248 0.74 ALDH1A1 (0.53) GABRA1GABRB2POLBMAPTKDM4E
SCHEMBL3807246 0.72 GABRA1 (0.46) GABRA1GABRB2POLBMAPTKDM4E
SCHEMBL12733027 0.72 GABRA1 (0.46) GABRA1GABRB2POLBMAPTKDM4E
SCHEMBL27862339 0.72 GABRA1 (0.46) GABRA1GABRB2POLBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127034-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-04-17 US disclosed
EP-4298135-B1 BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-16 EP disclosed
US-12069942-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-08-20 US disclosed
US-20240158542-A1 BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-16 US disclosed
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
EP-4298135-A1 BIS-PHENOXY-ETHER LIGANDS FOR GROUP IV POLYOLEFIN CATALYSIS Dow Global Technologies LLC (US) 2024-01-03 EP disclosed
CN-115804260-A Light-emitting device, light-emitting apparatus, electronic apparatus, and lighting apparatus 株式会社半导体能源研究所 2023-03-14 CN disclosed
CN-115699999-A Light-emitting device, display panel, light-emitting device, display device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2023-02-03 CN disclosed
CN-115417775-A Material for hole transport layer, material for electron blocking layer, material for electron transport layer, material for hole blocking layer, and light-emitting device 株式会社半导体能源研究所 2022-12-02 CN disclosed
CN-115380099-A Organic light emitting compound and organic light emitting device including the same 株式会社P&H TECH 2022-11-22 CN disclosed
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2017-02-23 US disclosed
EP-3133078-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2017-02-22 EP disclosed
US-20140183485-A1 BLUE FLUORESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE DEVICES USING THE SAME LG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed
US-8716524-B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same NAGASE & CO., LTD (JP) 2014-05-06 US disclosed
US-8697910-B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same NAGASE & CO., LTD (JP) 2014-04-15 US disclosed
US-20110152562-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & CO., LTD. (JP) 2011-06-23 US disclosed
US-7928224-B2 Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same NAGASE & CO., LTD (JP) 2011-04-19 US disclosed
US-20070161624-A1 Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same KISHIDA CHEMICAL CO., LTD. (JP) 2007-07-12 US disclosed
US-20070135654-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & CO., LTD (JP) 2007-06-14 US disclosed
EP-1712549-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME NAGASE & COMPANY, LTD. (JP) 2006-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135654-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME BCAT1, BCAT2, AADAT GABRA1 1879/4885GABRB2 2252/4885POLB 622/4885
US-12069942-B2 Organometallic compound and organic light-emitting device including the same CRY1, LEF1, POU2F1 GABRA1 1707/4885GABRB2 3078/4885POLB 3041/4885
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LAGE3, CRY1, LEF1 GABRA1 2731/4885GABRB2 3786/4885POLB 3601/4885
US-20110152562-A1 OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME BCAT1, AADAT, BCAT2 GABRA1 2215/4885GABRB2 2678/4885POLB 895/4885
US-20250127034-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OR10J3, OCIAD1, RO60 GABRA1 4254/4885GABRB2 4408/4885POLB 2034/4885
US-20070161624-A1 Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same BCAT1, BCAT2, AADAT GABRA1 1879/4885GABRB2 2252/4885POLB 622/4885
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 GABRA1 1707/4885GABRB2 3078/4885POLB 3041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.