Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | HTRA1 | Q92743 | 11/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.45 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872221 | 0.85 | DPP4 (0.52) | TGM2DPP4DPP8DPP7NMUR2 | |
| SCHEMBL17439162 | 0.82 | OPRM1 (0.49) | NMUR2NMUR1F2 | |
| SCHEMBL9450497 | 0.80 | DPP4 (0.47) | TGM2DPP4DPP8DPP7NMUR2 | |
| SCHEMBL7402735 | 0.80 | ACE (0.55) | DPP4DPP8PRSS1DPP7TMPRSS11D | |
| SCHEMBL7402728 | 0.80 | ACE (0.55) | DPP4DPP8PRSS1DPP7TMPRSS11D | |
| SCHEMBL18619636 | 0.79 | MALT1 (0.55) | DPP4DPP8PRSS1F2 | |
| SCHEMBL27543280 | 0.78 | DPP4 (0.45) | DPP4DPP8F10PLGPRSS1 | |
| SCHEMBL7982004 | 0.78 | PREP (0.49) | HTRA1 | |
| SCHEMBL5264694 | 0.78 | PREP (0.55) | — | |
| SCHEMBL13409461 | 0.78 | DPP4 (0.46) | TGM2DPP4DPP8F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791071-B1 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS INC (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0791071-A1 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS, INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5571684-A | SOLID PHASE CONJUGATE | LITMUS CONCEPTS, INC. (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996015255-A2 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS, INC. (US) | 1996-05-23 | — | — | WO | disclosed |