SCHEMBL8418693

SCHEMBL8418693

CCN(CCc1ccccc1)CC(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.51
OPRM1 P35372 2/20 0.51
DRD3 P35462 2/20 0.51
KCNH2 Q12809 2/20 0.51
CHRM2 P08172 1/20 0.51
HTR1A P08908 1/20 0.51
ADRA2A P08913 1/20 0.51
CHRM1 P11229 1/20 0.51
DRD1 P21728 1/20 0.51
SLC6A2 P23975 1/20 0.51
SLC6A4 P31645 1/20 0.51
ADRA1A P35348 1/20 0.51
SLC6A3 Q01959 1/20 0.51
CA12 O43570 4/20 0.49
CA1 P00915 4/20 0.49
CA2 P00918 4/20 0.49
CA4 P22748 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
GAA P10253 1/20 0.48
ACHE P22303 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13994260 0.83 OPRM1 (0.51) AOC3OPRM1DRD3KCNH2CHRM2
SCHEMBL8415629 0.83 LMNA (0.51) CA12CA1CA2L3MBTL1ACHE
SCHEMBL14228167 0.81 OPRM1 (0.49) AOC3OPRM1DRD3KCNH2CHRM2
SCHEMBL443493 0.80 OPRM1 (0.69) AOC3OPRM1DRD3KCNH2CHRM2
SCHEMBL11546029 0.80 OPRM1 (0.76) AOC3OPRM1DRD3KCNH2CHRM2
SCHEMBL14045656 0.80 ALOX5 (0.52) OPRM1DRD3KCNH2CHRM2HTR1A
Hydrochloric Acid SCHEMBL27864255 0.78 OPRM1 (0.67) AOC3OPRM1DRD3KCNH2CHRM2
Water SCHEMBL8191777 0.78 OPRM1 (0.67) AOC3OPRM1DRD3KCNH2CHRM2
SCHEMBL14342105 0.77 ALDH1A1 (0.59) AOC3OPRM1DRD3KCNH2CHRM2
SCHEMBL8589943 0.76 DRD2 (0.56) OPRM1DRD3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714885-B1 Preparation process of aminoacetamide derivative EISAI CO LTD (JP) 1999-09-01 EP disclosed
EP-0714885-A2 Preparation process of aminoacetamide derivative EISAI CHEMICAL CO., LTD. (JP) 1996-06-05 EP disclosed