Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13541712 | 0.84 | L3MBTL1 (0.51) | LTA4HACHECA12CA1CA2 | |
| SCHEMBL1491714 | 0.84 | ALOX5 (0.46) | ALOX5LTA4HSMN1; SMN2ABCB1PPID | |
| SCHEMBL14660352 | 0.83 | ALOX5 (0.60) | ALOX5OPRM1DRD3LTA4HL3MBTL1 | |
| SCHEMBL3184733 | 0.82 | ALDH1A1 (0.54) | ALOX5LTA4HL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10188366 | 0.82 | ALOX5 (0.44) | ALOX5LTA4HACHECA1CA2 | |
| SCHEMBL254781 | 0.81 | ALDH1A1 (0.53) | ALOX5LTA4HL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20506778 | 0.80 | ALDH1A1 (0.49) | ALOX5LTA4HACHEL3MBTL1SMN1; SMN2 | |
| SCHEMBL13994260 | 0.80 | OPRM1 (0.51) | SCN1ASCN2ASCN3ACHRM2HTR1A | |
| SCHEMBL8418693 | 0.80 | AOC3 (0.51) | SCN1ASCN2ASCN3ACHRM2HTR1A | |
| SCHEMBL14024656 | 0.79 | ALOX5 (0.50) | ALOX5LTA4HL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | ALOX5 4039/4885SCN1A 2134/4885SCN2A 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.