Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | DVL1 | O14640 | 1/20 | 0.48 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419001 | 0.86 | KDM4E (0.57) | ALDH1A1HSD17B10KDM4EPOLBCASP6 | |
| SCHEMBL8422575 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10KDM4EPOLBCASP6 | |
| SCHEMBL8420658 | 0.84 | SMN1; SMN2 (0.52) | ALDH1A1HSD17B10KDM4EPOLBCASP6 | |
| SCHEMBL8768524 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL8420661 | 0.80 | HTT (0.55) | POLBSMN1; SMN2HCAR2HTTRAB9A | |
| SCHEMBL8422577 | 0.79 | HTT (0.54) | KDM4EPOLBSMN1; SMN2GAAHCAR2 | |
| SCHEMBL3556661 | 0.78 | L3MBTL1 (0.65) | ALDH1A1HSD17B10POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL15648677 | 0.75 | MEN1 (0.80) | ALDH1A1HSD17B10KDM4EPOLBL3MBTL1 | |
| SCHEMBL14075194 | 0.75 | DVL1 (0.78) | ALDH1A1HSD17B10KDM4EL3MBTL1MEN1 | |
| SCHEMBL6032429 | 0.74 | HCAR2 (0.81) | ALDH1A1HSD17B10KDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |