Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 15/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427434 | 0.86 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL8427078 | 0.78 | GPR84 (0.46) | SNCATRPV1 | |
| SCHEMBL8533206 | 0.77 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL9293943 | 0.77 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL5190804 | 0.73 | TAS1R3 (0.50) | TRPV1 | |
| SCHEMBL8422984 | 0.72 | HTR7 (0.42) | SNCAHTR7 | |
| SCHEMBL8427410 | 0.72 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL5431339 | 0.72 | HTR7 (0.60) | SNCAHTR7 | |
| SCHEMBL4773611 | 0.71 | — | — | |
| SCHEMBL8533704 | 0.71 | TRPV1 (0.54) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863873-B1 | INDOLE CARBAMATES AS LEUKOTRIENE ANTAGONISTS | PFIZER (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5965745-A | ASTHMA; ANTIARTHRITIC,-SHOCK AGENTS; BRONCHITIS; RESPIRATORY SYSTEM DISEASES, E.G. CHRONIC OBSTRUCTIVE AIRWAYS DISEASES; PSORIASIS; ALLERGIC RHINITIS; ATOPIC DERMATITIS | PFIZER INC (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0863873-A1 | INDOLE CARBAMATES AS LEUKOTRIENE ANTAGONISTS | PFIZER INC. (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997013751-A1 | INDOLE CARBAMATES AS LEUKOTRIENE ANTAGONISTS | PFIZER INC. (US) | 1997-04-17 | — | — | WO | disclosed |