Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303615 | 0.81 | SCN5A (0.49) | SCN5ASCN9AMMP9MMP1MMP3 | |
| SCHEMBL7308906 | 0.78 | MMP9 (0.51) | SCN5ASCN9AMMP9MMP1MMP3 | |
| SCHEMBL8425309 | 0.76 | CYP3A4 (0.39) | MEN1KMT2ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL8315425 | 0.76 | OPRD1 (0.54) | SCN5ASCN9AMMP9MMP1MMP3 | |
| SCHEMBL12050043 | 0.72 | SCN5A (0.50) | SCN5ASCN9AMMP9MMP1MMP3 | |
| SCHEMBL7308120 | 0.71 | OPRK1 (0.47) | SCN5ASCN9AKDM1AMEN1KMT2A | |
| SCHEMBL2592306 | 0.71 | MEN1 (0.59) | SCN5ASCN9AKDM1AMEN1KMT2A | |
| SCHEMBL24199876 | 0.71 | SIGMAR1 (0.68) | KDM1ACYP2D6TSHRHTT | |
| SCHEMBL12050040 | 0.71 | HTT (0.49) | SCN5ASCN9AMMP9MMP1MMP3 | |
| SCHEMBL6608659 | 0.70 | SCN5A (0.52) | SCN5ASCN9AMMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |