Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR4 | P46093 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304915 | 0.90 | L3MBTL1 (0.42) | KDM1AGPR119USP30MAPTNPSR1 | |
| SCHEMBL7831649 | 0.82 | GPR119 (0.49) | KDM1AGPR119USP30CHRM2CHRM3 | |
| SCHEMBL7831085 | 0.78 | ALDH1A1 (0.50) | KDM1AGPR119TACR1OPRD1OPRK1 | |
| SCHEMBL19617505 | 0.78 | USP2 (0.38) | USP30TACR1OPRD1OPRK1SCD5 | |
| SCHEMBL7832576 | 0.77 | GPR119 (0.48) | KDM1AGPR119CHRM2CHRM3TACR1 | |
| SCHEMBL7839366 | 0.77 | GPR119 (0.48) | KDM1AGPR119CHRM2CHRM3TACR1 | |
| SCHEMBL7832066 | 0.76 | GPR119 (0.47) | KDM1AGPR119CHRM2CHRM3TACR1 | |
| SCHEMBL7831653 | 0.76 | PKM (0.53) | KDM1AGPR119TACR1OPRD1OPRK1 | |
| SCHEMBL7974238 | 0.75 | L3MBTL1 (0.47) | KDM1AGPR119TACR1OPRD1OPRK1 | |
| SCHEMBL26125344 | 0.73 | MEN1 (0.40) | GPR119TACR1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965578-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-10-12 | — | — | US | disclosed |