Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423589 | 0.90 | DRD4 (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8424027 | 0.88 | ALDH1A1 (0.36) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8423725 | 0.78 | HSD17B10 (0.34) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8425466 | 0.78 | DRD4 (0.46) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL31432963 | 0.73 | HRH2 (0.42) | ALDH1A1MAPTSMN1; SMN2NPSR1OPRM1 | |
| SCHEMBL15897489 | 0.72 | ACACB (0.44) | ALDH1A1MAPTSMN1; SMN2NPSR1OPRM1 | |
| SCHEMBL8423700 | 0.69 | HSD11B1 (0.37) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL28603385 | 0.68 | KMT2A (0.49) | ALDH1A1HPGDMAPTRAB9ANPSR1 | |
| SCHEMBL8424170 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2L3MBTL1HSD17B10 | |
| SCHEMBL28594379 | 0.65 | ELANE (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |