Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423725 | 0.89 | HSD17B10 (0.34) | ALDH1A1DRD4HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8425466 | 0.89 | DRD4 (0.46) | ALDH1A1DRD4HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8424173 | 0.88 | ALDH1A1 (0.36) | ALDH1A1DRD4HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8423700 | 0.80 | HSD11B1 (0.37) | ALDH1A1HSD17B10HPGDNPC1RAB9A | |
| SCHEMBL8423589 | 0.78 | DRD4 (0.41) | ALDH1A1DRD4HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8425305 | 0.70 | MMP1 (0.37) | ALDH1A1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL19110513 | 0.69 | LDHA (0.44) | ALDH1A1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL16468401 | 0.67 | MAP4K4 (0.42) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8424025 | 0.67 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL8423694 | 0.64 | PPARG (0.37) | ALDH1A1DRD4HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |