Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424068 | 0.90 | DRD4 (0.43) | DRD4HPGDALDH1A1LMNAHSD17B10 | |
| SCHEMBL8424027 | 0.89 | ALDH1A1 (0.36) | DRD4HPGDALDH1A1LMNAHSD17B10 | |
| SCHEMBL8423725 | 0.89 | HSD17B10 (0.34) | DRD4HPGDALDH1A1LMNAHSD17B10 | |
| SCHEMBL8423589 | 0.88 | DRD4 (0.41) | DRD4HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL8424173 | 0.78 | ALDH1A1 (0.36) | DRD4HPGDALDH1A1HSD17B10POLB | |
| SCHEMBL8425305 | 0.70 | MMP1 (0.37) | HPGDALDH1A1LMNAHSD17B10MMP2 | |
| SCHEMBL8426096 | 0.70 | MMP1 (0.38) | ALDH1A1LMNAMMP2MMP3MMP9 | |
| SCHEMBL31117784 | 0.70 | MAP4K4 (0.49) | HPGDALDH1A1LMNAMAP4K4MMP2 | |
| SCHEMBL697540 | 0.69 | MAP4K4 (0.53) | HPGDMAP4K4MMP13MEN1KMT2A | |
| SCHEMBL8423700 | 0.69 | HSD11B1 (0.37) | HPGDALDH1A1LMNAHSD17B10MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |