SCHEMBL8424844

SCHEMBL8424844

NNC(=O)c1c(O)cccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.52
CA2 P00918 5/20 0.52
CA9 Q16790 5/20 0.52
CA12 O43570 4/20 0.52
CA7 P43166 4/20 0.52
CA14 Q9ULX7 4/20 0.52
TAS1R3 Q7RTX0 1/20 0.52
TAS1R1 Q7RTX1 1/20 0.52
TAS1R2 Q8TE23 1/20 0.52
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
THRB P10828 1/20 0.50
PPIA P62937 3/20 0.49
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
MITF O75030 1/20 0.47
KMT2A Q03164 1/20 0.47
NCOA1 Q15788 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182679 0.87 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL1638645 0.86 CES2 (0.48) CA1CA2CA9CA12CA7
SCHEMBL12473715 0.86 ALDH1A1 (0.47) CA1CA2CA9CA12CA7
SCHEMBL28484554 0.84 G6PD (0.53) CA1CA2CA9CA12CA7
SCHEMBL5471293 0.81 ALDH1A1 (0.48) CA1CA2CA9CA12CA7
SCHEMBL23387407 0.79 ALDH1A1 (0.48) CA1CA2CA9ALDH1A1KDM4E
SCHEMBL28972091 0.78 CA1 (0.42) CA1CA2CA9CA12CA7
SCHEMBL10432360 0.78 GAA (0.47) CA1CA2CA9CA12CA7
SCHEMBL3918261 0.78 KDM4E (0.58) CA1CA2CA9CA12CA7
SCHEMBL723254 0.77 TERT (0.61) CA1CA2CA9ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119320519-A Rubber composite material, rubber compound and preparation method thereof 青岛黑猫新材料研究院有限公司 2025-01-17 CN claimed
EP-3805306-B1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2023-12-27 EP claimed
US-11708480-B2 Rubber composition, tire, additive and hydrazide compound OTSUKA CHEMICAL CO., LTD. (JP) 2023-07-25 US claimed
CN-109563316-B Rubber composition, tire, additive and hydrazide compound 株式会社普利司通 2021-08-17 CN claimed
EP-3805306-A1 RUBBER COMPOSITION AND TIRE Bridgestone Corporation (JP) 2021-04-14 EP claimed
EP-3495415-B1 RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND BRIDGESTONE CORP (JP) 2021-01-20 EP claimed
WO-2019156093-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2019-08-15 WO claimed
WO-2019156094-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2019-08-15 WO claimed
US-20190177513-A1 RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE BRIDGESTONE CORPORATION (JP) 2019-06-13 US claimed
EP-3495415-A1 RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND Bridgestone Corporation (JP) 2019-06-12 EP claimed
JP-11292834-A None JP disclosed
EP-4079805-B1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER IND (JP) 2026-02-18 EP disclosed
CN-119320519-A Rubber composite material, rubber compound and preparation method thereof 青岛黑猫新材料研究院有限公司 2025-01-17 CN disclosed
EP-3805306-B1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2023-12-27 EP disclosed
US-11708480-B2 Rubber composition, tire, additive and hydrazide compound OTSUKA CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed
US-20190177513-A1 RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE BRIDGESTONE CORPORATION (JP) 2019-06-13 US disclosed
EP-3495415-A1 RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND Bridgestone Corporation (JP) 2019-06-12 EP disclosed
EP-3495415-A1 RUBBER COMPOSITION, TIRE, ADDITIVE, AND HYDRAZIDE COMPOUND Bridgestone Corporation (JP) 2019-06-12 EP disclosed
CN-109563316-A Rubber composition, tire, additive and hydrazide compound 株式会社普利司通 2019-04-02 CN disclosed
JP-H11292834-A HYDRAZONE DERIVATIVE OTSUKA CHEM CO LTD 1999-10-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177513-A1 RUBBER COMPOSITION, TIRE, ADDITIVE AND HYDRAZIDE HRH2, HRH1, HEATR1 CA1 3503/4885CA2 3917/4885CA9 4222/4885
US-11708480-B2 Rubber composition, tire, additive and hydrazide compound HRH2, HRH1, HEATR1 CA1 3693/4885CA2 3980/4885CA9 4064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.