Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427024 | 0.86 | PGR (0.60) | PGRNR3C1LMNAARCYP3A4 | |
| SCHEMBL8425073 | 0.79 | PGR (0.49) | PGRNR3C1HIF1AMEN1LMNA | |
| SCHEMBL9322215 | 0.71 | PGR (0.46) | PGRNR3C1HIF1AMEN1LMNA | |
| SCHEMBL8427242 | 0.71 | PGR (0.81) | PGRNR3C1HIF1ALMNACYP2C19 | |
| SCHEMBL8427053 | 0.69 | PGR (0.81) | PGRNR3C1HIF1ALMNACYP2C19 | |
| SCHEMBL6512260 | 0.69 | ALDH1A1 (0.46) | PGRNR3C1HIF1AMEN1LMNA | |
| SCHEMBL8423175 | 0.68 | PGR (1.00) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8424832 | 0.68 | PGR (0.79) | PGRNR3C1HIF1ALMNACYP2C19 | |
| SCHEMBL8423021 | 0.67 | PGR (0.62) | PGRNR3C1HIF1AMEN1LMNA | |
| SCHEMBL8427168 | 0.66 | AR (0.64) | PGRNR3C1HIF1ALMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582338-B1 | 17-Spiromethylene steroids | AKZO NOBEL NV (NL) | 1999-10-20 | — | — | EP | disclosed |
| US-5854235-A | 17-spiromethylene steroids | AKZO NOBEL N.V. (NL) | 1998-12-29 | — | — | US | disclosed |
| US-5712264-A | 17-spiromethylene steroids | AKZO NOBEL N.V. (NL) | 1998-01-27 | — | — | US | disclosed |
| EP-0582338-A2 | 17-Spiromethylene steroids | Akzo Nobel N.V. (NL) | 1994-02-09 | — | — | EP | disclosed |