Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MMP10 | P09238 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427523 | 0.88 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EPOLBMEN1 | |
| SCHEMBL8425288 | 0.88 | ALDH1A1 (0.38) | FKBP1AALDH1A1SMN1; SMN2MMP1MMP2 | |
| SCHEMBL8423588 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDPOLBMEN1 | |
| SCHEMBL11865348 | 0.72 | HTT (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDPOLB | |
| SCHEMBL8425464 | 0.71 | S1PR5 (0.44) | FKBP1AALDH1A1S1PR5HPGDMEN1 | |
| SCHEMBL8424066 | 0.71 | HPGD (0.43) | ALDH1A1SMN1; SMN2S1PR5HPGDMMP1 | |
| SCHEMBL2409029 | 0.69 | MMP1 (0.50) | FKBP1AALDH1A1SMN1; SMN2KDM4EMMP1 | |
| SCHEMBL7709916 | 0.68 | TEAD1 (0.56) | FKBP1AALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL7302178 | 0.68 | MMP1 (0.46) | FKBP1AALDH1A1SMN1; SMN2POLBMMP1 | |
| SCHEMBL11540586 | 0.67 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |