Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424170 | 0.90 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8424066 | 0.90 | HPGD (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL8425464 | 0.86 | S1PR5 (0.44) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL8423721 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL8424025 | 0.75 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL8425539 | 0.74 | FKBP1A (0.42) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL8426091 | 0.71 | MMP2 (0.47) | SMN1; SMN2KMT2A | |
| SCHEMBL7409066 | 0.69 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8423589 | 0.67 | DRD4 (0.41) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31381177 | 0.66 | P2RX3 (0.57) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |