Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427417 | 0.92 | TDP1 (0.58) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL1983179 | 0.84 | ADRB2 (0.66) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL8429393 | 0.82 | ALDH1A1 (0.53) | ADRB2ADRB1ADRB3MAPK1SMN1; SMN2 | |
| SCHEMBL9463643 | 0.82 | LPAR1 (0.71) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| Phenylbutanoic Acid SCHEMBL406962 | 0.81 | ADRB2 (0.62) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL29028798 | 0.79 | LPAR1 (0.70) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL11293636 | 0.79 | LPAR1 (0.70) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL15061844 | 0.79 | MGLL (0.61) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL28226601 | 0.78 | ADRB2 (0.61) | ADRB2ADRB1ADRB3LPAR1TDP1 | |
| SCHEMBL15048863 | 0.78 | ADRB2 (0.58) | ADRB2ADRB1ADRB3LPAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773949-B1 | D-MANNOSE OR XYLITOL ESTERS AND THEIR USE AS DRUGS | ASSOCIAZIONE DI VOLONTARIATO P (IT) | 1999-11-10 | — | — | EP | claimed |
| US-5830872-A | THERAPY FOR BLOOD DISORDERS | L'ASSOCIAZIONE DI VOLONTARIATO "PRO LA FONDAZIONE FUTURO SENZA THALASSEMIA" (IT) | 1998-11-03 | — | — | US | claimed |
| US-5830872-A | THERAPY FOR BLOOD DISORDERS | L'ASSOCIAZIONE DI VOLONTARIATO "PRO LA FONDAZIONE FUTURO SENZA THALASSEMIA" (IT) | 1998-11-03 | — | — | US | disclosed |