Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425305 | 0.86 | MMP1 (0.37) | HSD11B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL8423694 | 0.85 | PPARG (0.37) | HSD11B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL8423700 | 0.83 | HSD11B1 (0.37) | HSD11B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL8426096 | 0.74 | MMP1 (0.38) | HSD11B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL8428006 | 0.72 | MMP2 (0.39) | PPARDMMP1MMP2MMP3MMP9 | |
| SCHEMBL7302175 | 0.67 | MMP1 (0.53) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL8423725 | 0.64 | HSD17B10 (0.34) | HSD11B1ALDH1A1DRD4 | |
| SCHEMBL7303000 | 0.61 | MMP1 (0.70) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL2766671 | 0.61 | ADAMTS5 (0.72) | MMP1ADAM17KAT6AGRIA2CYP2E1 | |
| SCHEMBL2766668 | 0.61 | ADAMTS5 (0.72) | MMP1ADAM17KAT6AGRIA2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |