Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP10 | P09238 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425305 | 0.82 | MMP1 (0.37) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8424068 | 0.81 | DRD4 (0.43) | ALDH1A1TMEM97SIGMAR1LMNAL3MBTL1 | |
| SCHEMBL8423700 | 0.80 | HSD11B1 (0.37) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8428008 | 0.74 | HSD11B1 (0.35) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8423694 | 0.74 | PPARG (0.37) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8423589 | 0.72 | DRD4 (0.41) | ABCB11ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL696193 | 0.70 | HPGD (0.43) | MMP13ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8426091 | 0.67 | MMP2 (0.47) | MMP1MMP2ABCB11MMP3MMP7 | |
| SCHEMBL27530823 | 0.65 | MMP1 (0.44) | MMP1MMP2ABCB11MMP3MMP7 | |
| SCHEMBL28596203 | 0.65 | HPGD (0.57) | ABCB11ALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |