Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278269 | 0.93 | KEAP1 (0.55) | MAPTKEAP1MEN1KMT2A | |
| SCHEMBL29450506 | 0.93 | KEAP1 (0.55) | MAPTKEAP1MEN1KMT2A | |
| SCHEMBL278767 | 0.89 | AMY1A (0.44) | — | |
| SCHEMBL29450504 | 0.89 | BCL2 (0.59) | MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL278522 | 0.89 | BCL2 (0.59) | MEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL29368767 | 0.87 | HSPA5 (0.43) | MAPTMEN1KMT2A | |
| SCHEMBL35864 | 0.87 | HSPA5 (0.43) | MAPTMEN1KMT2A | |
| SCHEMBL278275 | 0.84 | MAPT (0.45) | MAPTBCL2BCL2L1 | |
| SCHEMBL7776274 | 0.82 | CYP2C9 (0.46) | MAPTMEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL15313710 | 0.82 | LTA4H (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945516-A | PRIOR TO ESTERIFICATION OF THE POLYHYDROXY PHENOL WITH THE NAPHTHOQUINONE DIAZIDE SULFONYL HALIDE, THE REACTANTS ARE INITIALLY DISSOLVED IN AN APROTIC SOLVENT TOGETHER WITH STRONG BASE; NONPRECIPITATING, FOR FORMATION OF PHOTORESISTS | SHIPLEY COMPANY, L.L.C. (US) | 1999-08-31 | — | — | US | disclosed |
| US-5821345-A | DISSOLVING WITH A STRONG BASE AND APROTIC SOLVENT; ESTER INTERCHANGE | SHIPLEY COMPANY, L.L.C. (US) | 1998-10-13 | — | — | US | disclosed |