Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430807 | 0.93 | CA12 (0.35) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL8429288 | 0.90 | CA2 (0.38) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL8432878 | 0.88 | ITGB3 (0.39) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL8429051 | 0.86 | SIRT2 (0.36) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL8431173 | 0.86 | CTSD (0.35) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL8432438 | 0.83 | RAB9A (0.37) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL8431432 | 0.82 | RAB9A (0.36) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8431230 | 0.82 | RAB9A (0.40) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8431034 | 0.81 | ALDH1A1 (0.41) | RAB9ALMNAMAPTUSP2ALDH1A1 | |
| SCHEMBL8429155 | 0.80 | ITGB3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952381-A | SELECTIVELY INHIBITING OR ANTAGONIZING THE INTEGRINS; ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS, VIRICIDES, MICROBIOCIDES; TREATING OSTEOPOROSIS, SKIN DISORDERS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |