Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589528 | 0.88 | MMP9 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL6592827 | 0.85 | ALDH1A1 (0.33) | KDM4EPKMALDH1A1 | |
| SCHEMBL6592054 | 0.82 | CYP3A4 (0.30) | — | |
| SCHEMBL6587765 | 0.77 | LMNA (0.34) | LMNAKDM4ENAMPTALDH1A1 | |
| SCHEMBL6593566 | 0.73 | RXFP1 (0.37) | LMNAALDH1A1 | |
| SCHEMBL8432083 | 0.71 | RXFP1 (0.35) | LMNAALDH1A1 | |
| SCHEMBL6589332 | 0.64 | RXFP1 (0.49) | LMNAKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL6590388 | 0.63 | SLC6A2 (0.31) | — | |
| Fumaric Acid SCHEMBL8433463 | 0.63 | HRH1 (0.42) | LMNAKDM4EL3MBTL1ALDH1A1 | |
| Maleic Acid SCHEMBL8433458 | 0.63 | HRH1 (0.42) | LMNAKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874583-A | TREATING DEPRESSION, OBSESSIVE COMPULSIVE DISORDER, STUTTERING, TRICHOTILLOMANIA | HOECHST MARION ROUSSEL INC. (US) | 1999-02-23 | — | — | US | disclosed |