Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 4/20 | 0.30 |
| ▸ | DRD3 | P35462 | 4/20 | 0.30 |
| ▸ | DRD4 | P21917 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433919 | 0.79 | HTR2B (0.34) | HTR2BDRD2DRD3DRD4 | |
| SCHEMBL8436852 | 0.75 | MTNR1A (0.38) | OPRD1DRD2DRD3DRD4 | |
| SCHEMBL8434686 | 0.74 | ADRA2A (0.33) | — | |
| Oxalic Acid SCHEMBL8432169 | 0.71 | MTNR1A (0.39) | OPRD1DRD2DRD3DRD4 | |
| SCHEMBL10196253 | 0.63 | HTR2A (0.41) | HTR2BOPRD1DRD2DRD3DRD4 | |
| SCHEMBL8435308 | 0.61 | ADRA2A (0.43) | DRD2 | |
| Dimethylamine SCHEMBL8433452 | 0.61 | OPRD1 (0.38) | HTR2BOPRD1 | |
| SCHEMBL10551933 | 0.59 | HDAC3 (0.41) | — | |
| SCHEMBL7344800 | 0.59 | ALDH1A1 (0.41) | OPRD1 | |
| SCHEMBL8697680 | 0.59 | MTNR1A (0.36) | OPRD1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972964-A | FOR TREATMENT OF CERTAIN PSYCHIC AND NEUROLOGIC DISORDERS SUCH AS PSYCHOSIS, ANXIETY DISORDERS, PANIC DISORDER, OBSESSIVE COMPULSIVE DISORDER, DEPRESSION, IMPULSE CONTROL DISORDERS, ALCOHOL ABUSE, AGGRESSION | H. LUNDBECK A/S (DK) | 1999-10-26 | — | — | US | disclosed |
| US-5807889-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | H. LUNDBECK A/S (DK) | 1998-09-15 | — | — | US | disclosed |
| EP-0673360-B1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | LUNDBECK & CO AS H (DK) | 1998-08-26 | — | — | EP | disclosed |
| EP-0673360-A1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | H. LUNDBECK A/S (DK) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013620-A1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | H. LUNDBECK A/S (DK) | 1994-06-23 | — | — | WO | disclosed |