Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 8/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853432 | 0.83 | KCNA3 (0.55) | KCNA3HTTALDH1A1GAAPKM | |
| SCHEMBL8435929 | 0.80 | KCNA3 (0.64) | KCNA3ALDH1A1GAAPKMKDM4E | |
| SCHEMBL4393225 | 0.80 | KCNA3 (0.59) | KCNA3HTTALDH1A1GAAPKM | |
| SCHEMBL20529368 | 0.77 | KCNA3 (0.60) | KCNA3ALDH1A1GAAPKMKDM4E | |
| SCHEMBL13903718 | 0.74 | HTT (0.43) | KCNA3HTTALDH1A1GAAPKM | |
| SCHEMBL13903579 | 0.74 | HTT (0.43) | KCNA3HTTALDH1A1GAAPKM | |
| SCHEMBL27183175 | 0.73 | HTT (1.00) | HTTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL14374689 | 0.73 | PKM (0.57) | KCNA3HTTALDH1A1GAAPKM | |
| SCHEMBL13903626 | 0.72 | HSD17B10 (0.43) | KCNA3HTTALDH1A1GAAPKM | |
| SCHEMBL4383084 | 0.71 | LMNA (0.56) | KCNA3KDM4EHSD17B10NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952282-A | ADDING A 1,1-DIOXIDE, 3-(SUBSTITUTED AMINO)-1,2-BENZOISOTHIAZOLE COMPOUND TO BLEACH AS A BLEACH CATALYST | CLARIANT GMBH (DE) | 1999-09-14 | — | — | US | disclosed |