Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615124 | 0.89 | LMNA (0.49) | LMNANPC1KCNA3HPGDHSD17B10 | |
| SCHEMBL8435929 | 0.75 | KCNA3 (0.64) | LMNANPC1KCNA3HPGDKMT2A | |
| SCHEMBL20529368 | 0.72 | KCNA3 (0.60) | LMNANPC1KCNA3HPGDKMT2A | |
| SCHEMBL4393225 | 0.72 | KCNA3 (0.59) | LMNANPC1KCNA3KMT2AKDM4E | |
| SCHEMBL8436388 | 0.71 | KCNA3 (0.63) | LMNANPC1KCNA3HPGDHSD17B10 | |
| SCHEMBL13615748 | 0.71 | LMNA (0.56) | LMNANPC1HPGDHSD17B10KMT2A | |
| SCHEMBL11131932 | 0.70 | PKM (0.51) | LMNANPC1KCNA3HPGDHSD17B10 | |
| Saccharin SCHEMBL7361433 | 0.69 | ALDH1A1 (0.53) | LMNAKCNA3HPGDHSD17B10KMT2A | |
| SCHEMBL27273632 | 0.69 | HSD17B10 (0.49) | LMNAHPGDHSD17B10PKLR | |
| SCHEMBL11024449 | 0.68 | HSD17B10 (0.71) | LMNANPC1KCNA3HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |