Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.57 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.57 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529368 | 0.85 | KCNA3 (0.60) | KCNA3NPC1LMNAKMT2AMEN1 | |
| SCHEMBL8436388 | 0.80 | KCNA3 (0.63) | KCNA3NPC1LMNAKMT2AMEN1 | |
| SCHEMBL4393225 | 0.77 | KCNA3 (0.59) | KCNA3NPC1LMNAKMT2AALDH1A1 | |
| SCHEMBL11090203 | 0.75 | ALDH1A1 (0.46) | KCNA3NPC1LMNAKMT2AMEN1 | |
| SCHEMBL4383084 | 0.75 | LMNA (0.56) | KCNA3NPC1LMNAKMT2AMEN1 | |
| SCHEMBL3853432 | 0.74 | KCNA3 (0.55) | KCNA3NPC1LMNAKMT2AMEN1 | |
| SCHEMBL652970 | 0.74 | PKM (0.53) | KCNA3LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL20529044 | 0.72 | MEN1 (0.77) | KCNA3LMNAKMT2AMEN1TNNI3 | |
| SCHEMBL13903712 | 0.72 | KCNA3 (0.38) | KCNA3NPC1LMNAKMT2AMEN1 | |
| SCHEMBL13903578 | 0.72 | RET (0.40) | KCNA3NPC1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952282-A | ADDING A 1,1-DIOXIDE, 3-(SUBSTITUTED AMINO)-1,2-BENZOISOTHIAZOLE COMPOUND TO BLEACH AS A BLEACH CATALYST | CLARIANT GMBH (DE) | 1999-09-14 | — | — | US | disclosed |
| US-4104388-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-08-01 | — | — | US | disclosed |