Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436388 | 0.80 | KCNA3 (0.63) | KCNA3LMNAALDH1A1GAAHTT | |
| SCHEMBL8435929 | 0.77 | KCNA3 (0.64) | KCNA3LMNAALDH1A1GAAKMT2A | |
| SCHEMBL4383084 | 0.72 | LMNA (0.56) | KCNA3LMNAKMT2ANPC1KDM4E | |
| SCHEMBL4391092 | 0.72 | KCNA3 (0.39) | KCNA3LMNAALDH1A1KMT2APKM | |
| SCHEMBL20529368 | 0.71 | KCNA3 (0.60) | KCNA3LMNAALDH1A1GAAKMT2A | |
| SCHEMBL3853432 | 0.71 | KCNA3 (0.55) | KCNA3LMNAALDH1A1GAAHTT | |
| SCHEMBL10167479 | 0.69 | TP53 (0.41) | KCNA3LMNAALDH1A1GAAHTT | |
| SCHEMBL13615124 | 0.69 | LMNA (0.49) | KCNA3LMNAALDH1A1KMT2APKM | |
| SCHEMBL14374689 | 0.67 | PKM (0.57) | KCNA3LMNAALDH1A1GAAHTT | |
| SCHEMBL10167477 | 0.66 | TP53 (0.35) | KCNA3LMNAALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |