Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.64 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084456 | 0.79 | MMP1 (0.42) | SRD5A2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12157433 | 0.79 | KMT2A (0.53) | MEN1KMT2A | |
| SCHEMBL8070858 | 0.78 | SRD5A2 (1.00) | SRD5A2RARBMEN1KMT2A | |
| SCHEMBL8433248 | 0.78 | SRD5A2 (0.59) | SRD5A2ALDH1A1MAPTRXRARXRB | |
| SCHEMBL8719485 | 0.76 | ADRB1 (0.58) | SRD5A2RARBALDH1A1MEN1RARA | |
| SCHEMBL15651246 | 0.76 | OPRK1 (0.43) | ALDH1A1 | |
| SCHEMBL14958584 | 0.76 | TDP1 (0.57) | ALDH1A1KMT2A | |
| SCHEMBL8084537 | 0.76 | KMT2A (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3440360 | 0.75 | ALDH1A1 (0.55) | SRD5A2RARBALDH1A1MEN1MAPT | |
| SCHEMBL9369118 | 0.74 | ADRB3 (0.56) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |