Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910103 | 0.83 | PKM (0.77) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL6243131 | 0.81 | PKM (0.72) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL8437480 | 0.80 | PKM (1.00) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL11024449 | 0.74 | HSD17B10 (0.71) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL7738030 | 0.73 | ALDH1A1 (0.79) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL8036127 | 0.73 | RAB9A (0.63) | PKMALDH1A1GAAHSD17B10LMNA | |
| Probenazol SCHEMBL30425932 | 0.73 | PKM (0.65) | PKMALDH1A1GAAHSD17B10LMNA | |
| Probenazol SCHEMBL8409812 | 0.73 | PKM (0.65) | PKMALDH1A1GAAHSD17B10LMNA | |
| Probenazol SCHEMBL23516 | 0.73 | PKM (0.65) | PKMALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL11343161 | 0.71 | PKM (0.61) | PKMALDH1A1GAAHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952282-A | ADDING A 1,1-DIOXIDE, 3-(SUBSTITUTED AMINO)-1,2-BENZOISOTHIAZOLE COMPOUND TO BLEACH AS A BLEACH CATALYST | CLARIANT GMBH (DE) | 1999-09-14 | — | — | US | disclosed |