Probenazol

Probenazol

SCHEMBL23516

C=CCOC1=NS(=O)(=O)c2ccccc21

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.65
ALDH1A1 P00352 3/20 0.54
LMNA P02545 2/20 0.51
GAA P10253 3/20 0.49
HSD17B10 Q99714 3/20 0.49
HTT P42858 1/20 0.49
KDM4E B2RXH2 2/20 0.47
MAPT P10636 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RAB9A P51151 1/20 0.44
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
RHOA P61586 1/20 0.43
KCNA3 P22001 4/20 0.41
PTPRC P08575 1/20 0.41
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Probenazol SCHEMBL8409812 1.00 PKM (0.65) PKMALDH1A1LMNAGAAHSD17B10
Probenazol SCHEMBL30425932 1.00 PKM (0.65) PKMALDH1A1LMNAGAAHSD17B10
Probenazol SCHEMBL3027350 0.92 PKM (0.56) PKMALDH1A1LMNAGAAHSD17B10
Probenazol SCHEMBL28877681 0.81 PKM (0.44) PKMALDH1A1LMNAGAAHSD17B10
Probenazol SCHEMBL28097551 0.80 PKM (0.44) PKMALDH1A1LMNAGAAKDM4E
Thiophanate Methyl SCHEMBL28220504 0.79 HSD17B10 (0.51) PKMALDH1A1LMNAGAAHSD17B10
SCHEMBL8437480 0.79 PKM (1.00) PKMALDH1A1LMNAGAAHSD17B10
Thiophanate Methyl SCHEMBL28115100 0.78 PKM (0.45) PKMALDH1A1LMNAGAAHSD17B10
Isoprothiolane SCHEMBL9239101 0.78 PKM (0.44) PKMALDH1A1LMNAGAAHSD17B10
SCHEMBL6910103 0.76 PKM (0.77) PKMALDH1A1LMNAGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27916 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
WO-2026105160-A1 NOVEL AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2026-05-21 WO claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20260068884-A1 COMPOSITION USED FOR KILLING FUNGI AND METHOD FOR APPLYING COMPOSITION JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) 2026-03-12 US claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-4646109-A2 NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS Invaio Sciences, Inc. (US) 2025-11-12 EP claimed
WO-1996027290-A1 FUNGICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-12 WO claimed
US-5468747-A Fungicidal compositions and methods of use employing pyrimidine derivatives ZENECA LIMITED (GB) 1995-11-21 US claimed
CN-1104845-A Agricultural and/or horticultural fungicidal composition SUMITOMO CHEMICAL CO (JP) 1995-07-12 CN claimed
EP-0642502-A1 FUNGICIDAL IMIDAZOLINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-15 EP claimed
WO-1993024467-A1 FUNGICIDAL IMIDAZOLINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-09 WO claimed
EP-0478195-A1 Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM AND HAAS COMPANY (US) 1992-04-01 EP claimed
CN-1049771-A Composition pesticide ICI PLC (GB) 1991-03-13 CN claimed
EP-0415569-A2 Agrochemical compositions ZENECA LIMITED (GB) 1991-03-06 EP claimed
EP-0281911-A2 Stabilized composition Takeda Chemical Industries, Ltd. (JP) 1988-09-14 EP claimed
US-4731385-A NITROMETHYLENE DERIVATIVE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-03-15 US claimed