Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL9124695 | 0.91 | CCR5 (0.36) | DPP8DPP9RAB9ANPC1 | |
| SCHEMBL9728223 | 0.88 | DPP8 (0.46) | DPP8DPP9NPBWR1MCHR1 | |
| SCHEMBL8835181 | 0.88 | KCNJ1 (0.37) | DPP8DPP9NPBWR1MCHR1KCNJ1 | |
| SCHEMBL9119637 | 0.87 | DPP8 (0.45) | DPP8DPP9NPBWR1MCHR1RAB9A | |
| Trifluoromethanesulfonic Acid SCHEMBL8435997 | 0.86 | DPP8 (0.36) | DPP8DPP9NPBWR1MCHR1 | |
| SCHEMBL9042781 | 0.86 | HRH2 (0.39) | NPBWR1MCHR1KCNJ1KCNH2 | |
| SCHEMBL8438589 | 0.85 | KCNJ1 (0.42) | KCNJ1KCNH2 | |
| SCHEMBL8536750 | 0.85 | KCNJ1 (0.42) | KCNJ1KCNH2 | |
| SCHEMBL8541140 | 0.85 | RAB9A (0.41) | DPP8DPP9RAB9ANPC1 | |
| SCHEMBL8438677 | 0.85 | RAB9A (0.41) | DPP8DPP9RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |