Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442527 | 0.91 | ALDH1A1 (0.49) | ALDH1A1GAALMNAHTTKMT2A | |
| SCHEMBL8442980 | 0.89 | MMP2 (0.47) | ALDH1A1GAALMNAHTTKMT2A | |
| SCHEMBL8437964 | 0.88 | L3MBTL1 (0.53) | ALDH1A1GAALMNAHTTKMT2A | |
| SCHEMBL8441482 | 0.88 | ALDH1A1 (0.50) | ALDH1A1GAALMNAHTTTP53 | |
| SCHEMBL8440906 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TP53PKMPOLBSGMS1 | |
| SCHEMBL8438771 | 0.84 | KMT2A (0.53) | ALDH1A1GAALMNAHTTKMT2A | |
| SCHEMBL8441009 | 0.84 | CA1 (0.41) | ALDH1A1GAATAAR1LMNAHTT | |
| SCHEMBL8437801 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAALMNAKMT2AMEN1 | |
| SCHEMBL8440913 | 0.81 | TBXAS1 (0.51) | TDP1 | |
| SCHEMBL8443157 | 0.80 | MEP1B (0.49) | ALDH1A1GAALMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |