Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442527 | 0.86 | ALDH1A1 (0.49) | ALDH1A1LMNAGAASMN1; SMN2PKM | |
| SCHEMBL8442980 | 0.84 | MMP2 (0.47) | ALDH1A1LMNAGAAPKMMEN1 | |
| SCHEMBL8440592 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNAGAASMN1; SMN2PKM | |
| SCHEMBL8441482 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAKMT2ATBXAS1 | |
| SCHEMBL8437964 | 0.83 | L3MBTL1 (0.53) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL8440906 | 0.82 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL8443157 | 0.80 | MEP1B (0.49) | ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL8438771 | 0.80 | KMT2A (0.53) | ALDH1A1LMNAGAASLC1A3SLC1A2 | |
| SCHEMBL8439057 | 0.79 | VCAM1 (0.56) | ALDH1A1LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL8440913 | 0.79 | TBXAS1 (0.51) | SLC1A3SLC1A2SLC1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |