Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050306 | 0.80 | MAOB (0.39) | MAOAMAOBTOP1APP | |
| SCHEMBL1079030 | 0.74 | ALDH1A1 (0.46) | MAOAMAOBDAOKCNA3 | |
| SCHEMBL10446171 | 0.71 | GAPDH (0.53) | MAOAMAOBTOP1KCNA3RAB9A | |
| SCHEMBL1872240 | 0.71 | MAOA (1.00) | MAOAMAOBTOP1HSD17B3 | |
| SCHEMBL20087547 | 0.70 | MAOA (0.44) | MAOAMAOB | |
| SCHEMBL7898065 | 0.70 | ACHE (0.47) | MAOAMAOB | |
| Hydrochloric Acid SCHEMBL28528717 | 0.69 | MAOA (0.96) | MAOAMAOBTOP1HSD17B3 | |
| SCHEMBL11492402 | 0.69 | MAOA (0.44) | MAOAMAOB | |
| Bromide SCHEMBL27336436 | 0.69 | MAOA (0.96) | MAOAMAOBTOP1HSD17B3 | |
| Methane SCHEMBL16817136 | 0.69 | MAOA (0.96) | MAOAMAOBTOP1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758314-B1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LTD (GB) | 1999-09-15 | — | — | EP | claimed |
| WO-1995030646-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LIMITED (GB) | 1995-11-16 | — | — | WO | claimed |