Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438601 | 0.80 | CHRM5 (0.42) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8436212 | 0.76 | CYP11B2 (0.39) | MAPTCYP11B2CYP11B1HCAR2PADI4 | |
| SCHEMBL5252884 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTG6PDMAPK1NPSR1 | |
| SCHEMBL8488935 | 0.73 | RELA (0.42) | HTTALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL4540899 | 0.73 | HTT (0.50) | HTTALOX15ALDH1A1MAPTCYP11B2 | |
| SCHEMBL8485821 | 0.73 | VCP (0.41) | CYP11B2CYP11B1POLBRAB9AHCAR2 | |
| SCHEMBL13585158 | 0.73 | HTT (0.50) | HTTALOX15ALDH1A1MAPTCYP11B2 | |
| SCHEMBL4537053 | 0.73 | HTT (0.50) | HTTALOX15ALDH1A1MAPTCYP11B2 | |
| SCHEMBL2548845 | 0.72 | ATM (0.48) | ALDH1A1CYP11B2CYP11B1RAB9AMEN1 | |
| SCHEMBL7441695 | 0.71 | G6PD (0.54) | ALDH1A1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055703-A1 | 2-ALKYL-3-(HETERO)ARYL-8-AZABICYCLO[3.2.1]ALKANES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |