SCHEMBL844386

SCHEMBL844386

C=C(C)C(=O)OCCO[PH](C)=O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17407186 0.89 TSHR (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2721270 0.88 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL20956850 0.86 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL28738416 0.86 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1337099 0.86 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13144408 0.85 THRB (0.45) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13618829 0.84 TSHR (0.46) THRBTSHRALDH1A1POLBAPEX1
Butane SCHEMBL17350368 0.83 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15636 0.82 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6142874 0.82 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890264-B2 Metal oxide dispersion, polymerizable composition comprising the metal oxide dispersion, and polymer thereof OSAKA RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2018-02-13 US disclosed
US-9845394-B2 Method for producing thin film having high refractive index and high transparency, and thin film produced by the method OSAKA MUNICIPAL TECHNICAL RESEARCH INSTITUTE (JP) 2017-12-19 US disclosed
US-20170151158-A1 Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2017-06-01 US disclosed
US-20160338938-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-24 US disclosed
US-20160331668-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-17 US disclosed
US-20160331651-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-17 US disclosed
US-20160331667-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-17 US disclosed
US-20160331665-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-17 US disclosed
US-20160331669-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-17 US disclosed
US-20160331670-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2016-11-17 US disclosed
US-20080241754-A1 POLYONIUM BORATES AND RADIATION-SENSITIVE COMPOSITION AND IMAGEABLE ELEMENTS CONTAINING SAME BANK OF AMERICA, N.A., AS AGENT 2008-10-02 US disclosed
US-7429445-B1 Negative-working imageable elements and methods of use EASTMAN KODAK COMPANY (US) 2008-09-30 US disclosed
US-20080220365-A1 NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE FAR EAST DEVELOPMENT LTD. 2008-09-11 US disclosed
US-20080064233-A1 CIRCUIT-CONNECTING MATERIAL AND CIRCUIT TERMINAL CONNECTED STRUCTURE AND CONNECTING METHOD HITACHI CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed
US-20080054225-A1 interposed between circuit electrodes facing each other and electrically connects the electrodes in the pressing direction by pressing the facing electrodes against each other; the circuit-connecting material comprising as essential components, a curing agent and a hydroxy resin with radical polymer HITACHI CHEMICAL CO., LTD. (JP) 2008-03-06 US disclosed
US-20080057742-A1 CIRCUIT-CONNECTING MATERIAL AND CIRCUIT TERMINAL CONNECTED STRUCTURE AND CONNECTING METHOD HITACHI CHEMICAL CO., LTD. (JP) 2008-03-06 US disclosed
US-20080008957-A1 Negative-working radiation-sensitive compositions and imageable elements EASTMAN KODAK COMPANY 2008-01-10 US disclosed
US-20070299172-A1 interposed between circuit electrodes facing each other and electrically connects the electrodes in the pressing direction by pressing the facing electrodes against each other; the circuit-connecting material comprising as essential components, a curing agent and a hydroxy resin with radical polymer HITACHI CHEMICAL CO., LTD. (JP) 2007-12-27 US disclosed
US-7241644-B2 Adhesive, method of connecting wiring terminals and wiring structure HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-07-10 US disclosed
US-7175969-B1 Method of preparing negative-working radiation-sensitive elements EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160331667-A1 ORAL CARE COMPOSITIONS AND METHODS ALG1, FHIT, TAS2R39 THRB 3993/4885TSHR 4605/4885ALDH1A1 3813/4885
US-20160331668-A1 ORAL CARE COMPOSITIONS AND METHODS TAS2R40, TAS2R39, TAS2R30 THRB 3739/4885TSHR 4431/4885ALDH1A1 2353/4885
US-20160331669-A1 ORAL CARE COMPOSITIONS AND METHODS TAS2R39, TAS2R40, TAS2R9 THRB 1889/4885TSHR 2713/4885ALDH1A1 4457/4885
US-20080241754-A1 POLYONIUM BORATES AND RADIATION-SENSITIVE COMPOSITION AND IMAGEABLE ELEMENTS CONTAINING SAME XRCC5, BRAP, BRI3BP THRB 2146/4885TSHR 3303/4885ALDH1A1 4884/4885
US-20170151158-A1 Oral Care Compositions ARG1, SRM, ODC1 THRB 4127/4885TSHR 4381/4885ALDH1A1 4346/4885
US-20160338938-A1 ORAL CARE COMPOSITIONS AND METHODS SLC39A7, SLC39A3, SLC30A7 THRB 3947/4885TSHR 4460/4885ALDH1A1 3659/4885
US-20160331651-A1 ORAL CARE COMPOSITIONS AND METHODS ALG1, RPN1, TAS2R39 THRB 3247/4885TSHR 4500/4885ALDH1A1 2891/4885
US-20160331665-A1 ORAL CARE COMPOSITIONS AND METHODS TAS2R40, TAS2R39, TAS2R45 THRB 926/4885TSHR 954/4885ALDH1A1 4539/4885
US-20160331670-A1 ORAL CARE COMPOSITIONS AND METHODS ALG1, TAS2R39, KRTCAP2 THRB 3437/4885TSHR 4264/4885ALDH1A1 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.