⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467290 | 0.80 | — | — | |
| SCHEMBL7207522 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL7482639 | 0.70 | KMT2A (0.42) | — | |
| SCHEMBL7207584 | 0.68 | DRD2 (0.47) | — | |
| SCHEMBL7207516 | 0.68 | ADRA1D (0.46) | — | |
| SCHEMBL7207966 | 0.67 | KMT2A (0.51) | — | |
| SCHEMBL7473564 | 0.65 | KMT2A (0.39) | — | |
| SCHEMBL7467283 | 0.62 | KDM4E (0.32) | — | |
| SCHEMBL9190311 | 0.62 | MARS1 (0.40) | — | |
| SCHEMBL9188922 | 0.62 | MARS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923576-A1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008843-A1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |