Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922502 | 0.86 | HSD17B10 (0.50) | PTGS1PTGS2ESR1ESR2HSD17B10 | |
| SCHEMBL10826441 | 0.85 | ALOX5 (0.47) | PTGS1PTGS2ALOX5SIRT1SHBG | |
| SCHEMBL70636 | 0.84 | SHBG (0.55) | PTGS1PTGS2SIRT1SHBGESR1 | |
| SCHEMBL15368850 | 0.84 | PTGS1 (0.52) | PTGS1PTGS2SIRT1SHBGESR1 | |
| SCHEMBL1023068 | 0.84 | PTGS1 (0.55) | PTGS1PTGS2ALOX5SHBGESR1 | |
| SCHEMBL10415447 | 0.83 | PTGS2 (0.43) | PTGS1PTGS2SIRT1SHBGESR1 | |
| SCHEMBL3032085 | 0.83 | SHBG (0.53) | PTGS1PTGS2ALOX5SIRT1SHBG | |
| SCHEMBL14145128 | 0.81 | SIRT1 (0.39) | PTGS1PTGS2SIRT1SHBGHMGB1 | |
| SCHEMBL24450886 | 0.80 | TRPA1 (0.46) | PTGS1PTGS2ESR1ESR2HSD17B10 | |
| Bromide SCHEMBL4692089 | 0.79 | SIRT1 (0.38) | PTGS1PTGS2SIRT1SHBGHMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028058-B2 | Heterocyclic compounds as adenosine antagonists | NUVATION BIO INC. (US) | 2021-06-08 | — | — | US | disclosed |
| CN-112567509-A | Liquid compression moulding or encapsulant compositions | 汉高知识产权控股有限责任公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-107636039-B | Curing agent for thermosetting epoxy resins and method for producing insulation systems for electronic engineering | 亨斯迈先进材料许可(瑞士)有限公司 | 2020-11-24 | — | — | CN | disclosed |
| US-20190023666-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2019-01-24 | — | — | US | disclosed |
| CN-102892849-A | Curable powder coating composition and cured product thereof | NIPPON SODA CO | 2013-01-23 | — | — | CN | disclosed |
| CN-102455597-A | Radiation-sensitive resin composition, cured film and forming method thereof, array substrate of liquid crystal display element and forming method thereof | JSR CORP | 2012-05-16 | — | — | CN | disclosed |
| CN-102375338-A | Coloring composition, method for manufacturing the same, coloring pattern, color filter, color display component and method for manufacturing the color filter | JSR KK | 2012-03-14 | — | — | CN | disclosed |
| CN-101001887-B | Multi-branched polymer and method for producing same | NIPPON SODA CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-102298264-A | Radiation-sensitive resin composition for forming cured film, method of manufacturing the same, cured film, method for forming the cured film and display device | — | 2011-12-28 | — | — | CN | disclosed |
| CN-101593852-B | Multibranched polymers and process for production thereof | NIPPON SODA CO | 2011-03-02 | — | — | CN | disclosed |
| CN-101593852-A | Multibranched polymers and manufacture method thereof | NIPPON SODA CO (JP) | 2009-12-02 | — | — | CN | disclosed |
| US-7569725-B2 | 2-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]-5-phenoxybenzamide; therapeutic use as anti-cancer agents, as well as other therapeutic agents, for example, as anti-fertility agents | BRITSOL-MYERS SQUIBB COMPANY (US) | 2009-08-04 | — | — | US | disclosed |
| CN-101001887-A | Multi-branched polymer and method for producing same | NIPPON SODA CO (JP) | 2007-07-18 | — | — | CN | disclosed |
| EP-0709358-B1 | NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIFOULING AGENT | NIPPON SODA CO (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0816349-A1 | NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION CONTAINING SAID NOVEL CLATHRATE COMPOUND | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0709358-A1 | NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIFOULING AGENT | NIPPON SODA CO., LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023666-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | ADORA2A, ADORA3, ADORA1 | PTGS1 851/4885PTGS2 732/4885ALOX5 1239/4885 |
| US-11028058-B2 | Heterocyclic compounds as adenosine antagonists | ADORA2A, ADORA3, ADORA1 | PTGS1 851/4885PTGS2 732/4885ALOX5 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.