Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 11/20 | 0.62 |
| ▸ | MMP1 | P03956 | 8/20 | 0.62 |
| ▸ | MMP13 | P45452 | 8/20 | 0.62 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 8/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP16 | P51512 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448394 | 0.86 | MMP9 (0.67) | MMP9MMP1MMP13ADAM17MMP2 | |
| SCHEMBL8446284 | 0.85 | MMP9 (0.59) | MMP9MMP1MMP13ADAM17MMP2 | |
| SCHEMBL8446545 | 0.84 | ADAMTS4 (0.48) | MMP9MMP1MMP13ADAM17CYP2C9 | |
| SCHEMBL8445810 | 0.83 | MMP9 (0.46) | MMP9MMP1MMP13ADAM17CYP2C9 | |
| SCHEMBL8448315 | 0.81 | MMP9 (0.60) | MMP9MMP1MMP13ADAM17MMP2 | |
| SCHEMBL3941412 | 0.77 | ADAM17 (1.00) | MMP9MMP1MMP13ADAM17MMP2 | |
| SCHEMBL6879905 | 0.77 | ADAM17 (1.00) | MMP9MMP1MMP13ADAM17MMP2 | |
| SCHEMBL8446541 | 0.75 | MMP1 (0.60) | MMP9MMP1MMP13ADAM17CYP2C9 | |
| SCHEMBL8450950 | 0.75 | MMP1 (0.48) | MMP9MMP1MMP13ADAM17CA12 | |
| Hydrochloric Acid SCHEMBL8451752 | 0.74 | MMP1 (0.48) | MMP9MMP1MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |