Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445895 | 0.89 | MMP9 (0.47) | MMP9CA12CA2CA9BMP1 | |
| SCHEMBL8448553 | 0.83 | KEAP1 (0.50) | MMP9CA12CA2CA9BMP1 | |
| SCHEMBL8448544 | 0.81 | BMP1 (0.48) | MMP9CA12CA2CA9BMP1 | |
| SCHEMBL8450042 | 0.81 | MMP9 (0.44) | MMP9CA12CA2CA9BMP1 | |
| SCHEMBL8445701 | 0.80 | KEAP1 (0.53) | MMP9BMP1MMP2MMP13KEAP1 | |
| SCHEMBL8445759 | 0.80 | MMP9 (0.54) | MMP9CA12CA2CA9MMP2 | |
| SCHEMBL8448983 | 0.78 | POLB (0.45) | MMP9BMP1MMP2MMP13MMP3 | |
| SCHEMBL8448691 | 0.78 | MMP2 (0.47) | MMP9CA12CA9BMP1MMP2 | |
| SCHEMBL8445867 | 0.77 | MMP2 (0.48) | MMP9BMP1MMP2MMP13MMP8 | |
| SCHEMBL8446564 | 0.77 | ALDH1A1 (0.46) | MMP9BMP1MMP2MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |