Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.54 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911759 | 0.91 | AGER (0.59) | MMP9AGERCA12CA9MMP2 | |
| SCHEMBL8445657 | 0.87 | MMP9 (0.48) | MMP9AGERMMP13ADAMTS4MMP1 | |
| SCHEMBL8446042 | 0.85 | MMP9 (0.48) | MMP9AGERCA12CA9CA1 | |
| SCHEMBL8446284 | 0.85 | MMP9 (0.59) | MMP9AGERCA12CA9CA1 | |
| SCHEMBL8446545 | 0.84 | ADAMTS4 (0.48) | MMP9AGERCA12CA9CA1 | |
| SCHEMBL8446538 | 0.81 | MMP13 (0.44) | MMP9CA12CA9CA1CA2 | |
| SCHEMBL8448553 | 0.81 | KEAP1 (0.50) | MMP9CA12CA9CA1CA2 | |
| SCHEMBL8446648 | 0.80 | MMP9 (0.46) | MMP9CA12CA9CA1CA2 | |
| SCHEMBL8448544 | 0.79 | BMP1 (0.48) | MMP9CA12CA9CA1CA2 | |
| SCHEMBL8445701 | 0.78 | KEAP1 (0.53) | MMP9MMP2MMP13KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |