Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | STAT3 | P40763 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.57 |
| ▸ | SDHB | P21912 | 11/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | STAT1 | P42224 | 2/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830578 | 0.84 | SDHB (0.65) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL1067726 | 0.82 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL76774 | 0.77 | SDHB (0.60) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL8560362 | 0.76 | SDHB (0.56) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL15662202 | 0.76 | SDHB (0.56) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL8666206 | 0.75 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL6561352 | 0.75 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL5360302 | 0.75 | LMNA (0.78) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL8665226 | 0.75 | SDHB (0.58) | LMNASMN1; SMN2NPSR1HPGDTP53 | |
| SCHEMBL19805682 | 0.75 | NPSR1 (1.00) | LMNASMN1; SMN2NPSR1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628031-B1 | HERBICIDE N- (PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES | BASF AG (DE) | 1999-06-16 | — | — | EP | disclosed |
| US-5612286-A | FLUORINE SUBSTITUTED HEERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |
| EP-0628031-A1 | HERBICIDE N- (PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES | BASF Aktiengesellschaft (DE) | 1994-12-14 | — | — | EP | disclosed |
| US-5284820-A | Herbicidal substituted cycloalkenes | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| WO-1993016998-A1 | HERBICIDE N-[(PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-02 | — | — | WO | disclosed |
| EP-0532948-A1 | Substituted cycloalkenes as herbicides | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| EP-0285978-A2 | Substituted 1-(2-oxyaminosulfonyl-phenylsulfonyl)-3-(4-trifluoromethyl-pyrimidin-2-yl)-(thio)-ureas | BAYER AG (DE) | 1988-10-12 | — | — | EP | disclosed |