Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399525 | 0.89 | TSHR (0.34) | MTNR1AMTNR1BTSHR | |
| SCHEMBL8447931 | 0.83 | MTNR1A (0.33) | MTNR1AMTNR1BTSHR | |
| SCHEMBL8447280 | 0.80 | MTNR1A (0.33) | MTNR1AMTNR1BTSHR | |
| SCHEMBL16805864 | 0.79 | TSHR (0.38) | MTNR1AMTNR1BTSHR | |
| SCHEMBL8451742 | 0.78 | MTNR1A (0.33) | MTNR1AMTNR1BTSHR | |
| SCHEMBL339839 | 0.78 | TSHR (0.35) | MTNR1AMTNR1BTSHRMEN1KMT2A | |
| SCHEMBL24513273 | 0.75 | TGFBR1 (0.37) | MTNR1AMTNR1BTSHRMEN1KMT2A | |
| SCHEMBL20901035 | 0.73 | ALDH1A1 (0.38) | MTNR1AMTNR1BTSHR | |
| SCHEMBL11419538 | 0.73 | FAAH (0.36) | MTNR1AMTNR1BTSHR | |
| SCHEMBL10016884 | 0.73 | TSHR (0.32) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627942-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1999-09-15 | — | — | EP | disclosed |
| US-5795562-A | BIODEGRADABLE POLYMER AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | NYCOMED IMAGING AS (NO) | 1998-08-18 | — | — | US | disclosed |
| US-5676925-A | USING POLYESTER OR ACRYLATE POLYMERS | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5674468-A | A BIODEGRADABLE POLYESTER; USEFUL IN DIAGNOSTIC APPLICATIONS SUCH AS ULTRASOUND AND MAGNETIC RESONANCE IMAGING | NYCOMED IMAGING AS (NO) | 1997-10-07 | — | — | US | disclosed |
| US-5574097-A | NONCROSSLINKED POLYMERS WITH BIODEGRADABLE LIPOPHILIC SIDE CHAINS INCORPORATING METHYLENE DIESTER UNITS, CLEAVABLE TO YIELD A WATER SOLUBLE POLYMER | NYCOMED IMAGING AS (NO) | 1996-11-12 | — | — | US | disclosed |
| EP-0629214-B1 | CHEMICAL COMPOUNDS | NYCOMED IMAGING AS (NO) | 1996-10-23 | — | — | EP | disclosed |
| EP-0629214-A1 | CHEMICAL COMPOUNDS. | NYCOMED IMAGING AS (NO) | 1994-12-21 | — | — | EP | disclosed |
| EP-0627942-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017718-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993018070-A1 | CHEMICAL COMPOUNDS | NYCOMED IMAGING AS (NO) | 1993-09-16 | — | — | WO | disclosed |