Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845251 | 0.80 | PABPC1 (0.50) | KMT2AALDH1A1PABPC1TSHRHTT | |
| SCHEMBL845282 | 0.79 | CYP2C9 (0.47) | KMT2AALDH1A1RHOCRHOAPABPC1 | |
| SCHEMBL845295 | 0.78 | KDM4E (0.61) | KMT2AALDH1A1PABPC1TSHRNPSR1 | |
| SCHEMBL845338 | 0.78 | RHOC (0.48) | KMT2AALDH1A1RHOCRHOAPABPC1 | |
| SCHEMBL845367 | 0.77 | ALDH1A1 (0.47) | KMT2AALDH1A1TSHRNPSR1POLB | |
| SCHEMBL845341 | 0.77 | CYP2C9 (0.43) | KMT2AALDH1A1RHOCRHOAPOLB | |
| SCHEMBL845333 | 0.76 | PABPC1 (0.48) | KMT2AALDH1A1RHOCRHOAPABPC1 | |
| SCHEMBL845422 | 0.76 | KMT2A (0.46) | KMT2AALDH1A1RHOCRHOAPABPC1 | |
| SCHEMBL845008 | 0.76 | ALDH1A1 (0.54) | KMT2AALDH1A1TSHRNPSR1POLB | |
| SCHEMBL845570 | 0.76 | TP53BP1 (0.45) | ALDH1A1RHOCRHOAPABPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |