Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458292 | 0.84 | IKBKB (0.41) | IKBKBRARAHIF1AEPAS1CNR2 | |
| SCHEMBL8458293 | 0.83 | IKBKB (0.39) | IKBKBRARAHIF1AEPAS1MEN1 | |
| SCHEMBL8458404 | 0.80 | HIF1A (0.38) | IKBKBRARAHIF1AEPAS1MEN1 | |
| SCHEMBL8459014 | 0.77 | CNR2 (0.31) | HIF1AAVPR2AVPR1ACNR2 | |
| SCHEMBL8911209 | 0.72 | RARA (0.41) | RARAAVPR2AVPR1ACNR2LMNA | |
| SCHEMBL20565392 | 0.69 | IKBKB (0.47) | IKBKBRARAHIF1AEPAS1LMNA | |
| SCHEMBL31327303 | 0.68 | IKBKB (0.42) | IKBKBRARAHIF1AEPAS1CNR2 | |
| SCHEMBL11057929 | 0.68 | KCNA3 (0.54) | MEN1ALDH1A1KMT2AKDM1A | |
| SCHEMBL8909355 | 0.67 | MEN1 (0.42) | IKBKBRARACNR2MEN1ALDH1A1 | |
| SCHEMBL20565375 | 0.66 | IKBKB (0.48) | IKBKBRARAHIF1AEPAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |