SCHEMBL8463248

SCHEMBL8463248

CCS(=O)(=O)Nc1cc(-n2c(=O)cc(C(F)(F)F)n(N)c2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.33
PPOX P50336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8462175 0.89 PPOX (0.39) PPOX
SCHEMBL7833797 0.88 PSIP1 (0.33) PSIP1PPOX
SCHEMBL5868194 0.85 PGR (0.35) PSIP1
SCHEMBL8461149 0.82 AR (0.33) PSIP1
SCHEMBL8762906 0.82 BRAF (0.36)
SCHEMBL8122021 0.81 MCL1 (0.34) PSIP1
SCHEMBL9679435 0.80 PPOX (0.35) PPOX
SCHEMBL7821029 0.78 BRAF (0.30) PPOX
SCHEMBL22520007 0.78
SCHEMBL9123594 0.78 BCAT1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4346981-A None JP disclosed
US-5990044-A Selective herbicides based on aryl uracils BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
JP-H04346981-A PYRIMIDINE DERIVATIVE AND HERBICIDE NISSAN CHEM IND LTD 1992-12-02 JP disclosed